2-Fluoro-3-(trifluoromethyl)benzoic acid → 2-Fluoro-3-(trifluoromethyl)benzoyl chloride
Reaction equation
[F:1][C:2]1[C:10]([C:11]([F:14])([F:13])[F:12])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4](O)=[O:5].[Cl:15]C1C(C(F)(F)F)=CC=CC=1C(O)=O>>[F:1][C:2]1[C:10]([C:11]([F:14])([F:13])[F:12])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([Cl:15])=[O:5]Participants
3
Procedure
Intermediate 13 was prepared in a similar manner as Intermediate 12 substituting 2-fluoro-3-(trifluoromethyl)benzoic acid for 2-chloro-3-(trifluoromethyl)benzoic acid.
Sources & evidence
- ORD record
- ord-5590f228977340fc971a8f0273132a26
- Source dataset
- uspto-grants-2015_06
- Patent number
- US09066946B2
Reaction notes
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