2,3-Dichloro-4-fluorobenzoic acid → HCID 90408855, compound

HRID 2177612Notes

Reaction equation

HRID 2177612 reaction equation
[CH3:1][CH:2]1[NH:7][CH2:6][C:5]2[N:8]=[N:9][N:10]([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][N:12]=3)[C:4]=2[CH2:3]1.[Cl:17][C:18]1[C:26]([Cl:27])=[C:25]([F:28])[CH:24]=[CH:23][C:19]=1[C:20](O)=[O:21]>>[Cl:17][C:18]1[C:26]([Cl:27])=[C:25]([F:28])[CH:24]=[CH:23][C:19]=1[C:20]([N:7]1[CH:2]([CH3:1])[CH2:3][C:4]2[N:10]([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][N:12]=3)[N:9]=[N:8][C:5]=2[CH2:6]1)=[O:21]

Participants

3

Reactant 2

HCID 103307052,3-Dichloro-4-fluorobenzoic acidHCID 90408482HCID 90408482, compound

Product 1

HCID 90408855HCID 90408855, compound

Procedure

Example 121 was prepared from 6-methyl-1-(pyridin-2-yl)-4,5,6,7-tetrahydro-1H-[1,2,3]triazolo[4,5-c]pyridine and 2,3-dichloro-4-fluorobenzoic acid using the conditions described in Example 65. MS (ESI) mass calcd. C18H14Cl2FN5O, 405.06. m/z found, 406.1 [M+H]+.

Sources & evidence

ORD record
ord-a7fbb1b2567144d8adc3a883e23e7db0
Source dataset
uspto-grants-2015_06
Patent number
US09066946B2

Reaction notes

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