2-Chloro-3-(trifluoromethyl)benzoic acid → 2-Methyl-3-(trifluoromethyl)benzoyl chloride

HRID 2177630Notes

Reaction equation

HRID 2177630 reaction equation
Cl[C:2]1[C:10]([C:11]([F:14])([F:13])[F:12])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([Cl:6])=[O:5].[CH3:15]C1C(C(F)(F)F)=CC=CC=1C(O)=O.ClC1C(C(F)(F)F)=CC=CC=1C(O)=O>>[CH3:15][C:2]1[C:10]([C:11]([F:14])([F:13])[F:12])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([Cl:6])=[O:5]

Participants

4

Reactant 3

HCID 27366772-Chloro-3-(trifluoromethyl)benzoic acidHCID 27755842-Methyl-3-(trifluoromethyl)benzoic acidHCID 38276332-Chloro-3-(trifluoromethyl)benzoyl chloride

Product 1

HCID 27756022-Methyl-3-(trifluoromethyl)benzoyl chloride

Procedure

The title compound was prepared in a manner analogous to Intermediate 12 substituting 2-methyl-3-(trifluoromethyl)benzoic acid for 2-chloro-3-(trifluoromethyl)benzoic acid.

Sources & evidence

ORD record
ord-78b129f33138461d85dd7b2f95ec8d9e
Source dataset
uspto-grants-2015_06
Patent number
US09066946B2

Reaction notes

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