Aniline → 7-methyl-1-phenyl-1H-[1,2,3]triazolo[4,5-c]pyridine

HRID 2177643Notes

Reaction equation

HRID 2177643 reaction equation
Cl[C:2]1[C:7]([N+:8]([O-])=O)=[CH:6][N:5]=[CH:4][C:3]=1[CH3:11].ClC1C=C[N:16]=CC=1[N+]([O-])=O.[NH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1.NC1C=CC=CN=1>>[CH3:11][C:3]1[C:2]2[N:22]([C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)[N:16]=[N:8][C:7]=2[CH:6]=[N:5][CH:4]=1

Participants

5

Reactant 4

HCID 6115AnilineHCID 104392-AminopyridineHCID 27357814-Chloro-3-nitropyridineHCID 588823714-Chloro-3-methyl-5-nitropyridine

Product 1

HCID 904100647-methyl-1-phenyl-1H-[1,2,3]triazolo[4,5-c]pyridine

Procedure

The title compound was prepared in a manner analogous to Intermediate 17, Step 1 through Intermediate 19, Step 3 substituting 4-chloro-3-methyl-5-nitro-pyridine for 4-chloro-3-nitropyridine, and aniline for 2-aminopyridine. MS (ESI) mass calcd. C12H10N4, 210.1. m/z found, 225.1 [M+H]+.

Sources & evidence

ORD record
ord-c9f68a9b1b97435d892bcb3d42653eeb
Source dataset
uspto-grants-2015_06
Patent number
US09066946B2

Reaction notes

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