反应详情

A mixture of methyl 6-[2-(3-diethylaminoprop-1-en-1-yl)benzenesulphonyl-methyl]-3-(furan-3-yl)-2-methoxybenzoate (mixture of E and Z isomers, Intermediate 5, 0.03 g) and palladium on carbon (10%, 0.006 g) in methanol (1.2 ml) was stirred in an atmosphere of hydrogen (balloon) for 1 hour. The mixture was filtered through Celite and the filtrate was evaporated to dryness to give methyl 6-[2-(3-diethylaminopropyl)benzenesulphonylmethyl]-3-(furan-3-yl)-2-methoxybenzoate (0.028 g) as a colourless oil.

1. filtrationThe mixture was filtered through Celite
2. customthe filtrate was evaporated to dryness