6-(Benzenesulphonylmethyl)-2-[2-(t-butoxycarbonyl)aminoethoxy]-3-(furan-3-yl)benzoic acid → 2-[2-(t-Butoxycarbonyl)aminoethoxy]-3-(furan-3-yl)-6-(2-methoxybenzenesulphonylmethyl)benzoic acid

HRID 2177692Notes

Reaction equation

HRID 2177692 reaction equation
C1(S(CC2C(C(O)=O)=C(OCCNC(OC(C)(C)C)=O)C(C3C=COC=3)=CC=2)(=O)=O)C=CC=CC=1.[C:36]([O:40][C:41]([NH:43][CH2:44][CH2:45][O:46][C:47]1[C:56]([C:57]2[CH:61]=[CH:60][O:59][CH:58]=2)=[CH:55][CH:54]=[C:53]([CH2:62][S:63]([C:66]2[CH:71]=[CH:70][CH:69]=[CH:68][C:67]=2[O:72][CH3:73])(=[O:65])=[O:64])[C:48]=1[C:49]([O:51]C)=[O:50])=[O:42])([CH3:39])([CH3:38])[CH3:37]>>[C:36]([O:40][C:41]([NH:43][CH2:44][CH2:45][O:46][C:47]1[C:56]([C:57]2[CH:61]=[CH:60][O:59][CH:58]=2)=[CH:55][CH:54]=[C:53]([CH2:62][S:63]([C:66]2[CH:71]=[CH:70][CH:69]=[CH:68][C:67]=2[O:72][CH3:73])(=[O:65])=[O:64])[C:48]=1[C:49]([OH:51])=[O:50])=[O:42])([CH3:39])([CH3:38])[CH3:37]

Participants

3

Reactant 2

HCID 671076826-(Benzenesulphonylmethyl)-2-[2-(t-butoxycarbonyl)aminoethoxy]-3-(furan-3-yl)benzoic acidHCID 67107991Methyl 2-[2-(t-butoxycarbonyl)aminoethoxy]-3-(furan-3-yl)-6-(2-methoxybenzenesulphonylmethyl)benzoate2×

Product 1

HCID 671073572-[2-(t-Butoxycarbonyl)aminoethoxy]-3-(furan-3-yl)-6-(2-methoxybenzenesulphonylmethyl)benzoic acid

Procedure

Prepared by proceeding in a similar manner to Intermediate 6, starting from methyl 2-[2-(t-butoxycarbonyl)aminoethoxy]-3-(furan-3-yl)-6-(2-methoxybenzenesulphonylmethyl)benzoate (Intermediate 14).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-6f0af7e1d61245e9aaa29a5f7e102cea
Source dataset
uspto-grants-2015_06
Patent number
US09067905B2

Reaction notes

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