Triethylborane → Ethyl 6-(phenylthiomethyl)-3-ethyl-2-methoxybenzoate

HRID 2177702Notes

Reaction equation

HRID 2177702 reaction equation
[CH2:1](C1C=C2C(COC2=O)=CC=1)[CH3:2].Br[C:14]1[C:15]([O:33][CH3:34])=[C:16]([C:22]([CH2:25][S:26][C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)=[CH:23][CH:24]=1)[C:17]([O:19][CH2:20][CH3:21])=[O:18].C(B(CC)CC)C>>[C:27]1([S:26][CH2:25][C:22]2[C:16]([C:17]([O:19][CH2:20][CH3:21])=[O:18])=[C:15]([O:33][CH3:34])[C:14]([CH2:1][CH3:2])=[CH:24][CH:23]=2)[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1

Participants

4

Reactant 3

HCID 7357TriethylboraneHCID 593824426-ethyl-3H-isobenzofuran-1-oneHCID 67107500HCID 67107500, compound2×

Product 1

HCID 67107436Ethyl 6-(phenylthiomethyl)-3-ethyl-2-methoxybenzoate

Procedure

Prepared by proceeding in a similar manner to Intermediate 18, starting from ethyl 3-bromo-6-(phenylthiomethyl)-2-methoxybenzoate (Intermediate 73) and triethyl borane.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-7b07ce0d636045a085033e11eac414e5
Source dataset
uspto-grants-2015_06
Patent number
US09067905B2

Reaction notes

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