Triethylborane → Ethyl 6-(4-chlorobenzenesulphonylmethyl)-3-ethyl-2-methoxybenzoate

HRID 2177704Notes

Reaction equation

HRID 2177704 reaction equation
[CH2:1](C1C=C2C(COC2=O)=CC=1)[CH3:2].[Cl:13][C:14]1[CH:19]=[CH:18][C:17]([S:20]([CH2:23][C:24]2[C:29]([C:30]([O:32][CH2:33][CH3:34])=[O:31])=[C:28]([O:35][CH3:36])[C:27](Br)=[CH:26][CH:25]=2)(=[O:22])=[O:21])=[CH:16][CH:15]=1.C(B(CC)CC)C>>[Cl:13][C:14]1[CH:19]=[CH:18][C:17]([S:20]([CH2:23][C:24]2[C:29]([C:30]([O:32][CH2:33][CH3:34])=[O:31])=[C:28]([O:35][CH3:36])[C:27]([CH2:1][CH3:2])=[CH:26][CH:25]=2)(=[O:22])=[O:21])=[CH:16][CH:15]=1

Participants

4

Reactant 3

HCID 7357TriethylboraneHCID 593824426-ethyl-3H-isobenzofuran-1-oneHCID 67107510Ethyl 6-(4-chlorobenzenesulphonylmethyl)-3-bromo-2-methoxybenzoate2×

Product 1

HCID 67107592Ethyl 6-(4-chlorobenzenesulphonylmethyl)-3-ethyl-2-methoxybenzoate

Procedure

Prepared by proceeding in a similar manner to Intermediate 18, starting from ethyl 6-(4-chlorobenzenesulphonylmethyl)-3-bromo-2-methoxybenzoate (Intermediate 84) and triethyl borane.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-b31ed146039d42d0b94a7a9827d4daeb
Source dataset
uspto-grants-2015_06
Patent number
US09067905B2

Reaction notes

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