HRID2177721

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2734358

Furan-3-boronic acid

C4H5BO3

反应SMILES：CCOC(=O)c1c(CS(=O)(=O)c2ccccc2)ccc(Br)c1OC

HCID67107394

未命名化合物

反应SMILES：COC(=O)c1cc(-c2cnco2)ccc1CS(=O)(=O)c1ccccc1

HCID67107594

未命名化合物

反应SMILES：COC(=O)c1c(CS(=O)(=O)c2ccccc2C=CCO)ccc(Br)c1OC

HCID67107632

未命名化合物

PRODUCTS

产物

反应SMILES：COC(=O)c1c(CS(=O)(=O)c2ccccc2C=CCO)ccc(-c2ccoc2)c1OC

HCID67107768

未命名化合物

PROCEDURE

实验过程

Prepared by proceeding in a similar manner to Intermediate 42, starting from methyl 3-bromo-6-((2-(3-hydroxyprop-1-enyl)benzenesulfonyl)methyl)-2-methoxybenzoate (mixture of E and Z isomers, Intermediate 60) and furan-3-yl boronic acid.

WORKUP

后处理

customPrepared

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-948889b4d37944fe8b0968f8980ba0aa
来源数据集: uspto-grants-2015_06
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US09067905B2
来源说明: uspto-grants-2015_06

反应SMILES

C1(S(CC2C=[CH:19][C:18]([C:21]3[O:25][CH:24]=NC=3)=CC=2C(OC)=O)(=O)=O)C=CC=CC=1.Br[C:27]1[C:28]([O:51][CH3:52])=[C:29]([C:34]([CH2:37][S:38]([C:41]2[CH:46]=[CH:45][CH:44]=[CH:43][C:42]=2[CH:47]=[CH:48][CH2:49][OH:50])(=[O:40])=[O:39])=[CH:35][CH:36]=1)[C:30]([O:32][CH3:33])=[O:31].C1(S(CC2C(C(OCC)=O)=C(OC)C(Br)=CC=2)(=O)=O)C=CC=CC=1.O1C=CC(B(O)O)=C1>>[O:25]1[CH:21]=[CH:18][C:19]([C:27]2[C:28]([O:51][CH3:52])=[C:29]([C:34]([CH2:37][S:38]([C:41]3[CH:46]=[CH:45][CH:44]=[CH:43][C:42]=3[CH:47]=[CH:48][CH2:49][OH:50])(=[O:39])=[O:40])=[CH:35][CH:36]=2)[C:30]([O:32][CH3:33])=[O:31])=[CH:24]1