Methyl 3-bromo-6-(3-chlorobenzenesulphonylmethyl)-2-hydroxybenzoate → Methyl 3-bromo-6-(4-fluorobenzenesulphonylmethyl)-2-hydroxybenzoate

HRID 2177728Notes

Reaction equation

HRID 2177728 reaction equation
BrC1C(O)=C(C(CS(C2C=CC=C(Cl)C=2)(=O)=O)=CC=1)C(OC)=O.[Br:24][C:25]1[C:26]([O:46]C)=[C:27]([C:32]([CH2:35][S:36]([C:39]2[CH:44]=[CH:43][C:42]([F:45])=[CH:41][CH:40]=2)(=[O:38])=[O:37])=[CH:33][CH:34]=1)[C:28]([O:30][CH3:31])=[O:29]>>[Br:24][C:25]1[C:26]([OH:46])=[C:27]([C:32]([CH2:35][S:36]([C:39]2[CH:40]=[CH:41][C:42]([F:45])=[CH:43][CH:44]=2)(=[O:38])=[O:37])=[CH:33][CH:34]=1)[C:28]([O:30][CH3:31])=[O:29]

Participants

3

Reactant 2

HCID 67107545Methyl 3-bromo-6-(3-chlorobenzenesulphonylmethyl)-2-hydroxybenzoateHCID 67107935Methyl 3-bromo-6-(4-fluorobenzenesulphonylmethyl)-2-methoxybenzoate2×

Product 1

HCID 67107667Methyl 3-bromo-6-(4-fluorobenzenesulphonylmethyl)-2-hydroxybenzoate

Procedure

Prepared by proceeding in a similar manner to Intermediate 54, starting from methyl 3-bromo-6-(4-fluorobenzenesulphonylmethyl)-2-methoxybenzoate (Intermediate 69).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-1db99f367a3844b6a76be57d7558bf3e
Source dataset
uspto-grants-2015_06
Patent number
US09067905B2

Reaction notes

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