Ethyl 6-(benzenesulphonylmethyl)-3-bromo-2-methoxybenzoate → Ethyl 3-bromo-6-(3-chlorobenzenesulphonylmethyl)-2-methoxybenzoate

HRID 2177735Notes

Reaction equation

HRID 2177735 reaction equation
[C:1]1([S:7]([CH2:10][C:11]2[C:16]([C:17]([O:19][CH2:20][CH3:21])=[O:18])=[C:15]([O:22][CH3:23])[C:14]([Br:24])=[CH:13][CH:12]=2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.BrC1C(OC)=C(C(CSC2C=CC=C([Cl:45])C=2)=CC=1)C(OCC)=O>>[Br:24][C:14]1[C:15]([O:22][CH3:23])=[C:16]([C:11]([CH2:10][S:7]([C:1]2[CH:2]=[CH:3][CH:4]=[C:5]([Cl:45])[CH:6]=2)(=[O:9])=[O:8])=[CH:12][CH:13]=1)[C:17]([O:19][CH2:20][CH3:21])=[O:18]

Participants

3

Reactant 2

HCID 67107394Ethyl 6-(benzenesulphonylmethyl)-3-bromo-2-methoxybenzoateHCID 67107689HCID 67107689, compound2×

Product 1

HCID 67107550Ethyl 3-bromo-6-(3-chlorobenzenesulphonylmethyl)-2-methoxybenzoate

Procedure

Prepared by proceeding in a similar manner to Intermediate 61, starting from ethyl 3-bromo-6-(3-chlorophenylthiomethyl)-2-methoxybenzoate (Intermediate 79).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-b28d1bcd897642f09daa1bb05d11e559
Source dataset
uspto-grants-2015_06
Patent number
US09067905B2

Reaction notes

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