Methyl 6-(benzenesulfonylmethyl)-3-bromo-2-methoxybenzoate → Methyl 6-(benzenesulfonylmethyl)-3-bromo-2-hydroxybenzoate

HRID 2177778Notes

Reaction equation

HRID 2177778 reaction equation
[Br:1][C:2]1[C:3]([OH:23])=[C:4]([C:9]([CH2:12][S:13]([C:16]2[CH:21]=[CH:20][CH:19]=[C:18](Cl)[CH:17]=2)(=[O:15])=[O:14])=[CH:10][CH:11]=1)[C:5]([O:7][CH3:8])=[O:6].C1(S(CC2C(C(OC)=O)=C(OC)C(Br)=CC=2)(=O)=O)C=CC=CC=1>>[C:16]1([S:13]([CH2:12][C:9]2[C:4]([C:5]([O:7][CH3:8])=[O:6])=[C:3]([OH:23])[C:2]([Br:1])=[CH:11][CH:10]=2)(=[O:15])=[O:14])[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1

Participants

3

Reactant 2

HCID 66685730Methyl 6-(benzenesulfonylmethyl)-3-bromo-2-methoxybenzoate2×HCID 67107545Methyl 3-bromo-6-(3-chlorobenzenesulphonylmethyl)-2-hydroxybenzoate

Product 1

HCID 66685467Methyl 6-(benzenesulfonylmethyl)-3-bromo-2-hydroxybenzoate

Procedure

Prepared by proceeding in a similar manner to Intermediate 54, starting from methyl 6-(benzenesulphonylmethyl)-3-bromo-2-methoxybenzoate (Intermediate 65).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-c5eb20e06c0d460785830623b1fd9191
Source dataset
uspto-grants-2015_06
Patent number
US09067905B2

Reaction notes

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