tert-butyl N-(1-hydroxypropan-2-yl)carbamate → HCID 67107710, compound

HRID 2177790Notes

Reaction equation

HRID 2177790 reaction equation
[C:1]1([S:7]([CH2:10][C:11]2[C:16]([C:17]([O:19][CH3:20])=[O:18])=[C:15]([O:21][CH2:22][CH2:23][N:24]([C:26]([O:28][C:29]([CH3:32])([CH3:31])[CH3:30])=[O:27])C)[C:14]([C:33]3[CH:37]=[CH:36][O:35][CH:34]=3)=[CH:13][CH:12]=2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:38]1(S(CC2C(C(O)=O)=C(O)C(C3C=COC=3)=CC=2)(=O)=O)C=CC=CC=1.C(OC(NC(C)CO)=O)(C)(C)C>>[C:1]1([S:7]([CH2:10][C:11]2[C:16]([C:17]([O:19][CH3:20])=[O:18])=[C:15]([O:21][CH2:22][CH:23]([NH:24][C:26]([O:28][C:29]([CH3:30])([CH3:31])[CH3:32])=[O:27])[CH3:38])[C:14]([C:33]3[CH:37]=[CH:36][O:35][CH:34]=3)=[CH:13][CH:12]=2)(=[O:8])=[O:9])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 3

HCID 545701tert-butyl N-(1-hydroxypropan-2-yl)carbamateHCID 52914186HCID 52914186, compound2×HCID 67107624Methyl 6-(benzenesulphonylmethyl)-2-[2-(N-t-butoxycarbonyl-N-methylamino)ethoxy]-3-(furan-3-yl)benzoate

Product 1

HCID 67107710HCID 67107710, compound

Procedure

Prepared by proceeding in a similar manner to Intermediate 125, starting from methyl 6-(benzenesulphonylmethyl)-3-(furan-3-yl)-2-hydroxybenzoate (Intermediate 114) and 2-(N-t-butoxycarbonylamino)-1-propanol as a white solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-a3773143db474a3b93d944d41f330b58
Source dataset
uspto-grants-2015_06
Patent number
US09067905B2

Reaction notes

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