1-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole → HCID 67107603, compound

HRID 2177795Notes

Reaction equation

HRID 2177795 reaction equation
[C:1]1([S:7]([CH2:10][C:11]2[CH:20]=[CH:19][C:18](Br)=[CH:17][C:12]=2[C:13]([O:15][CH3:16])=[O:14])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:22][N:23]1[C:27](B2OC(C)(C)C(C)(C)O2)=[CH:26][CH:25]=[N:24]1>>[C:1]1([S:7]([CH2:10][C:11]2[CH:20]=[CH:19][C:18]([C:27]3[N:23]([CH3:22])[N:24]=[CH:25][CH:26]=3)=[CH:17][C:12]=2[C:13]([O:15][CH3:16])=[O:14])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 49129081-methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleHCID 67107956Methyl 2-benzenesulphonylmethyl-5-bromobenzoate2×

Product 1

HCID 67107603HCID 67107603, compound

Procedure

Prepared by proceeding in a similar manner to Example 37, starting from methyl 2-(benzenesulphonylmethyl)-5-bromobenzoate (Intermediate 63) and 1-methyl-1H-pyrazole-5-boronic acid pinacol ester.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-fa5d20c19dba48edb13fadb886cc6fff
Source dataset
uspto-grants-2015_06
Patent number
US09067905B2

Reaction notes

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