Methyl 3-bromo-6-(3-hydroxyphenylthiomethyl)-2-methoxybenzoate → Methyl 3-bromo-6-(3-hydroxybenzenesulphonylmethyl)-2-methoxybenzoate

HRID 2177800Notes

Reaction equation

HRID 2177800 reaction equation
[Br:1][C:2]1[C:3]([O:23][CH3:24])=[C:4]([C:9]([CH2:12][S:13]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=2O)(=[O:15])=[O:14])=[CH:10][CH:11]=1)[C:5]([O:7][CH3:8])=[O:6].BrC1C(OC)=C(C(CSC2C=CC=C(O)C=2)=CC=1)C(OC)=[O:30]>>[Br:1][C:2]1[C:3]([O:23][CH3:24])=[C:4]([C:9]([CH2:12][S:13]([C:16]2[CH:21]=[CH:20][CH:19]=[C:18]([OH:30])[CH:17]=2)(=[O:15])=[O:14])=[CH:10][CH:11]=1)[C:5]([O:7][CH3:8])=[O:6]

Participants

3

Reactant 2

HCID 67107504Methyl 3-bromo-6-(3-hydroxyphenylthiomethyl)-2-methoxybenzoate2×HCID 67107647Methyl 3-bromo-6-(2-hydroxybenzenesulphonylmethyl)-2-methoxybenzoate

Product 1

HCID 67107640Methyl 3-bromo-6-(3-hydroxybenzenesulphonylmethyl)-2-methoxybenzoate

Procedure

Prepared by proceeding in a similar manner to Intermediate 138, starting from methyl 3-bromo-6-(3-hydroxyphenylthiomethyl)-2-methoxybenzoate (Intermediate 142).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-fecf129e6a474268878db097f8d34197
Source dataset
uspto-grants-2015_06
Patent number
US09067905B2

Reaction notes

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