3-Hydroxybenzenethiol → Methyl 3-bromo-6-(3-hydroxyphenylthiomethyl)-2-methoxybenzoate

HRID 2177801Notes

Reaction equation

HRID 2177801 reaction equation
BrC1C(O)=C(C(CSC2C=CC=CC=2OC)=CC=1)C(OC)=O.[Br:23][C:24]1[C:25]([O:36][CH3:37])=[C:26]([C:31]([CH2:34]Br)=[CH:32][CH:33]=1)[C:27]([O:29][CH3:30])=[O:28].[SH:38][C:39]1[CH:40]=[C:41]([OH:45])[CH:42]=[CH:43][CH:44]=1>>[Br:23][C:24]1[C:25]([O:36][CH3:37])=[C:26]([C:31]([CH2:34][S:38][C:39]2[CH:44]=[CH:43][CH:42]=[C:41]([OH:45])[CH:40]=2)=[CH:32][CH:33]=1)[C:27]([O:29][CH3:30])=[O:28]

Participants

4

Reactant 3

HCID 27366133-HydroxybenzenethiolHCID 66685947Methyl 3-bromo-6-bromomethyl-2-methoxybenzoate2×HCID 67107461Methyl 3-bromo-2-hydroxy-6-(2-methoxyphenylthiomethyl)benzoate

Product 1

HCID 67107504Methyl 3-bromo-6-(3-hydroxyphenylthiomethyl)-2-methoxybenzoate

Procedure

Prepared by proceeding in a similar manner to Intermediate 82, starting from methyl 3-bromo-6-bromomethyl-2-methoxybenzoate (Intermediate 89) and 3-mercaptophenol and used without further characterization.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-ca8e6b50a7464b3cb664bf8cf873a5c7
Source dataset
uspto-grants-2015_06
Patent number
US09067905B2

Reaction notes

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