Ethyl 6-benzenesulphonylmethyl-3-(furan-3-yl)-2-hydroxybenzoate → Methyl 6-(bicyclo[2.2.2]oct-5-ene-2-ylsulphonylmethyl)-3-(furan-3-yl)-2-methoxybenzoate

HRID 2177822Notes

Reaction equation

HRID 2177822 reaction equation
C1(S(CC2C(C(OCC)=O)=C(O)C([C:23]3[CH:27]=[CH:26][O:25][CH:24]=3)=CC=2)(=O)=O)C=CC=CC=1.[CH:28]12[CH2:35][CH2:34][CH:31]([CH:32]=[CH:33]1)[CH2:30][CH:29]2[S:36]([CH2:39][C:40]1[C:45]([C:46]([O:48][CH3:49])=[O:47])=[C:44]([O:50][CH3:51])[C:43](Br)=[CH:42][CH:41]=1)(=[O:38])=[O:37]>>[CH:28]12[CH2:35][CH2:34][CH:31]([CH:32]=[CH:33]1)[CH2:30][CH:29]2[S:36]([CH2:39][C:40]1[C:45]([C:46]([O:48][CH3:49])=[O:47])=[C:44]([O:50][CH3:51])[C:43]([C:23]2[CH:27]=[CH:26][O:25][CH:24]=2)=[CH:42][CH:41]=1)(=[O:38])=[O:37]

Participants

3

Reactant 2

HCID 67107629Ethyl 6-benzenesulphonylmethyl-3-(furan-3-yl)-2-hydroxybenzoateHCID 67107748Methyl 6-(bicyclo[2.2.2]oct-5-ene-2-ylsulphonylmethyl)-3-bromo-2-methoxybenzoate

Product 1

HCID 67107910Methyl 6-(bicyclo[2.2.2]oct-5-ene-2-ylsulphonylmethyl)-3-(furan-3-yl)-2-methoxybenzoate

Procedure

Prepared by proceeding in a similar manner to Intermediate 36, starting from methyl 6-(bicyclo[2.2.2]oct-5-ene-2-ylsulphonylmethyl)-3-bromo-2-methoxybenzoate.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-edbbecc3cce04537a03f3737d46b800e
Source dataset
uspto-grants-2015_06
Patent number
US09067905B2

Reaction notes

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