Ethyl 6-benzenesulphonylmethyl-3-(furan-3-yl)-2-hydroxybenzoate → HCID 69915006, compound

HRID 2177828Notes

Reaction equation

HRID 2177828 reaction equation
C1(S(CC2C(C(OCC)=O)=C(O)C([C:23]3[CH:27]=[CH:26][O:25][CH:24]=3)=CC=2)(=O)=O)C=CC=CC=1.Br[C:29]1[C:30]([O:51][CH3:52])=[C:31]([C:36]([CH2:39][S:40]([N:43]2[CH2:48][CH2:47][C:46]([F:50])([F:49])[CH2:45][CH2:44]2)(=[O:42])=[O:41])=[CH:37][CH:38]=1)[C:32]([O:34][CH3:35])=[O:33]>>[F:49][C:46]1([F:50])[CH2:47][CH2:48][N:43]([S:40]([CH2:39][C:36]2[C:31]([C:32]([O:34][CH3:35])=[O:33])=[C:30]([O:51][CH3:52])[C:29]([C:23]3[CH:27]=[CH:26][O:25][CH:24]=3)=[CH:38][CH:37]=2)(=[O:42])=[O:41])[CH2:44][CH2:45]1

Participants

3

Reactant 2

HCID 67107629Ethyl 6-benzenesulphonylmethyl-3-(furan-3-yl)-2-hydroxybenzoateHCID 67108006HCID 67108006, compound2×

Product 1

HCID 69915006HCID 69915006, compound

Procedure

Prepared by proceeding in a similar manner to Intermediate 36, starting from methyl 3-bromo-6-(4,4-difluoropiperidine-1-ylsulphonylmethyl)-2-methoxybenzoate (Intermediate 179), as a white solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-1440ab31c8834c9fa19f3f6e367911f4
Source dataset
uspto-grants-2015_06
Patent number
US09067905B2

Reaction notes

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