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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2177831Generated: November 2, 2026

Methylamine → Methyl 6-(benzenesulphonylmethyl)-3-(furan-3-yl)-2-methylaminobenzoate

https://huagongshe.com/reaction/2177831

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
ReactantMethyl 6-(benzenesulphonylmethyl)-2-[2-(t-butoxycarbonylamino)ethylamino]-3-(furan-3-yl)benzoateHCID 67108007—
ReactantMethyl 6-(benzenesulphonylmethyl)-3-(furan-3-yl)-2-(trifluoromethanesulphonyloxy)benzoateHCID 86677115—
SolventTetrahydrofuranHCID 8028—
ProductMethyl 6-(benzenesulphonylmethyl)-3-(furan-3-yl)-2-methylaminobenzoateHCID 67107559—

Reaction Steps

Prepared by proceeding in a similar manner to Intermediate 122, starting from methyl 6-(benzenesulphonylmethyl)-3-(furan-3-yl)-2-(trifluoromethanesulphonyloxy)-benzoate (Intermediate 123) and 2M methylamine in THF.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09067905B2
Source datasetuspto-grants-2015_06
ORD IDord-8a0797fae9354bcf9664a2cde4cc12f6
Source noteuspto-grants-2015_06