Ethyl 6-benzenesulphonylmethyl-3-(furan-3-yl)-2-hydroxybenzoate → HCID 67107626, compound

HRID 2177832Notes

Reaction equation

HRID 2177832 reaction equation
C1(S(CC2C(C(OCC)=O)=C(O)C([C:23]3[CH:27]=[CH:26][O:25][CH:24]=3)=CC=2)(=O)=O)C=CC=CC=1.[CH:28]12[N:35]([S:36]([CH2:39][C:40]3[C:45]([C:46]([O:48][CH3:49])=[O:47])=[C:44]([O:50][CH3:51])[C:43](Br)=[CH:42][CH:41]=3)(=[O:38])=[O:37])[CH:32]([CH2:33][CH2:34]1)[CH2:31][CH2:30][CH2:29]2>>[CH:28]12[N:35]([S:36]([CH2:39][C:40]3[C:45]([C:46]([O:48][CH3:49])=[O:47])=[C:44]([O:50][CH3:51])[C:43]([C:23]4[CH:27]=[CH:26][O:25][CH:24]=4)=[CH:42][CH:41]=3)(=[O:38])=[O:37])[CH:32]([CH2:33][CH2:34]1)[CH2:31][CH2:30][CH2:29]2

Participants

3

Reactant 2

HCID 67107629Ethyl 6-benzenesulphonylmethyl-3-(furan-3-yl)-2-hydroxybenzoateHCID 67107760HCID 67107760, compound2×

Product 1

HCID 67107626HCID 67107626, compound

Procedure

Prepared by proceeding in a similar manner to Intermediate 36, starting from methyl 6-(8-azabicyclo[3.2.1]octane-8-ylsulphonylmethyl)-3-bromo-2-methoxybenzoate (Intermediate 186) as a white solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-58e9effa54f942ee8397e52fcb7e5dbb
Source dataset
uspto-grants-2015_06
Patent number
US09067905B2

Reaction notes

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