Ethyl 3-iodo-2,4-dimethoxy-6-methylbenzoate → Ethyl 6-bromomethyl-3-iodo-2,4-dimethoxybenzoate

HRID 2177846Notes

Reaction equation

HRID 2177846 reaction equation
[Br:1]C1C(OC)=C(C(CSC2C=CC=CC=2)=CC=1)C(OCC)=O.[I:23][C:24]1[C:25]([O:38][CH3:39])=[C:26]([C:32]([CH3:37])=[CH:33][C:34]=1[O:35][CH3:36])[C:27]([O:29][CH2:30][CH3:31])=[O:28]>>[Br:1][CH2:37][C:32]1[C:26]([C:27]([O:29][CH2:30][CH3:31])=[O:28])=[C:25]([O:38][CH3:39])[C:24]([I:23])=[C:34]([O:35][CH3:36])[CH:33]=1

Participants

3

Reactant 2

HCID 10915077Ethyl 3-iodo-2,4-dimethoxy-6-methylbenzoate2×HCID 67107500HCID 67107500, compound

Product 1

HCID 86677124Ethyl 6-bromomethyl-3-iodo-2,4-dimethoxybenzoate

Procedure

Prepared by proceeding in a similar manner to Intermediate 87, starting from ethyl 3-iodo-2,4-dimethoxy-6-methylbenzoate (Intermediate 203).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-d9107393aae246eba434eeadb2405c6c
Source dataset
uspto-grants-2015_06
Patent number
US09067905B2

Reaction notes

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