Methyl 3-bromo-6-(phenylthiomethyl)-2-methoxybenzoate → Methyl 3-(furan-3-yl)-2-methoxy-6-(phenylthiomethyl)benzoate

HRID 2177858Notes

Reaction equation

HRID 2177858 reaction equation
[C:1]1([S:7]([CH2:10][C:11]2[C:16]([C:17]([O:19][CH2:20]C)=[O:18])=[C:15]([OH:22])[C:14]([C:23]3[CH:27]=[CH:26][O:25][CH:24]=3)=[CH:13][CH:12]=2)(=O)=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Br[C:29]1C(OC)=C(C(CSC2C=CC=CC=2)=CC=1)C(OC)=O>>[O:25]1[CH:26]=[CH:27][C:23]([C:14]2[C:15]([O:22][CH3:29])=[C:16]([C:11]([CH2:10][S:7][C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)=[CH:12][CH:13]=2)[C:17]([O:19][CH3:20])=[O:18])=[CH:24]1

Participants

3

Reactant 2

HCID 67107558Methyl 3-bromo-6-(phenylthiomethyl)-2-methoxybenzoate2×HCID 67107629Ethyl 6-benzenesulphonylmethyl-3-(furan-3-yl)-2-hydroxybenzoate

Product 1

HCID 67107588Methyl 3-(furan-3-yl)-2-methoxy-6-(phenylthiomethyl)benzoate

Procedure

Prepared by proceeding in a similar manner to Intermediate 36, starting from methyl 3-bromo-2-methoxy-6-(phenylthiomethyl)-benzoate (Intermediate 80) and used without further characterization.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-c88f588e8feb438d9e0d9c92a1dde662
Source dataset
uspto-grants-2015_06
Patent number
US09067905B2

Reaction notes

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