Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Nicotinic Acid | HCID 938 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | Nicotinoyl chloride | HCID 82604 | — |
Reaction Steps
To a solution of nicotinic acid (2 g, 16.2 mmol) in anhydrous THF (30 mL) was added SOCl2 (2.4 mL, 32.5 mmol). After stirring at 80° C. for 2 hours, the mixture was concentrated in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09067893B2 |
|---|
| Source dataset | uspto-grants-2015_06 |
|---|
| ORD ID | ord-1471c842a6284e72899ddb12b50eb920 |
|---|
| Source note | uspto-grants-2015_06 |
|---|
