HRID217808

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID17987855

未命名化合物

结构：CC(C)(C)OC(=O)Nc1ccc(Oc2ccnc3[nH]c(=O)cnc23)cc1

HCID46900574

未命名化合物

PRODUCTS

生成物

结构：Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc4[nH]c(=O)cnc34)cc2)cc1

HCID44133906

未命名化合物

收率 55%

PROCEDURE

实验过程

Method F1 was used with Tert-butyl 4-(3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yloxy)phenylcarbamate and 3-tert-butyl-5-isocyanato-1-p-tolyl-1H-pyrazole to obtain the title compound (yield 55%).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-d13ebafebb854877bef1a6732cc5a51c
来源数据集: uspto-grants-2012_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08198279B2
来源说明: uspto-grants-2012_06

反应 SMILES

[O:1]=[C:2]1[NH:7][C:6]2[N:8]=[CH:9][CH:10]=[C:11]([O:12][C:13]3[CH:18]=[CH:17][C:16]([NH:19][C:20](=O)[O:21]C(C)(C)C)=[CH:15][CH:14]=3)[C:5]=2[N:4]=[CH:3]1.[C:27]([C:31]1[CH:35]=[C:34]([N:36]=C=O)[N:33]([C:39]2[CH:44]=[CH:43][C:42]([CH3:45])=[CH:41][CH:40]=2)[N:32]=1)([CH3:30])([CH3:29])[CH3:28]>>[C:27]([C:31]1[CH:35]=[C:34]([NH:36][C:20]([NH:19][C:16]2[CH:15]=[CH:14][C:13]([O:12][C:11]3[C:5]4[N:4]=[CH:3][C:2](=[O:1])[NH:7][C:6]=4[N:8]=[CH:9][CH:10]=3)=[CH:18][CH:17]=2)=[O:21])[N:33]([C:39]2[CH:40]=[CH:41][C:42]([CH3:45])=[CH:43][CH:44]=2)[N:32]=1)([CH3:30])([CH3:29])[CH3:28]