Ethyl 2-(3-vinylphenyl)acetate → Ethyl 2-(3-ethylphenyl)acetate

HRID 2178087Notes

Reaction equation

HRID 2178087 reaction equation
[CH:1]([C:3]1[CH:4]=[C:5]([CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11])[CH:6]=[CH:7][CH:8]=1)=[CH2:2]>C(O)C.[Pd]>[CH2:1]([C:3]1[CH:4]=[C:5]([CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11])[CH:6]=[CH:7][CH:8]=1)[CH3:2]

Participants

4

Reactant 1

HCID 11687033Ethyl 2-(3-vinylphenyl)acetate

Product 1

HCID 59382622Ethyl 2-(3-ethylphenyl)acetateYield 77%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Conditions

Temperature
30 °C

Procedure

To a solution of ethyl 2-(3-vinylphenyl)acetate (640 mg, 3.6 mmol) in ethanol (10 mL) was added 10% of Pd/C (100 mg) and stirred at 30° C. under hydrogen atmosphere (15 psi) for 7 hours. Then the solution was filtered and the solvent was removed in vacuo (500 mg, yield 77%).

Workup

  1. filtrationThen the solution was filtered
  2. customthe solvent was removed in vacuo (500 mg, yield 77%)

Sources & evidence

ORD record
ord-6005ba9a255d4059ac2b01de347e9246
Source dataset
uspto-grants-2015_06
Patent number
US09067893B2

Reaction notes

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