Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | HCID 67060958 | HCID 67060958 | — |
| Product | HCID 21568243 | HCID 21568243 | — |
Reaction Steps
A mixture of ethyl 4-cyano-3,5-diethoxybenzoate (1.0 g, 3.8 mmol) and KOH (5.0 g, 89.3 mmol) in water (30 mL) was stirred at 130° C. overnight. The mixture was acidified with aqueous HCl (2M) until pH=5. Solvent removed in vacuo and used for next step directly without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09067893B2 |
|---|
| Source dataset | uspto-grants-2015_06 |
|---|
| ORD ID | ord-3b283288efcf4819b0f3eff5023b806b |
|---|
| Source note | uspto-grants-2015_06 |
|---|
