5-Chloro-2,4-difluorobenzenesulphonyl chloride → HCID 117653312, compound

HRID 2178128Notes

Reaction equation

HRID 2178128 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[CH:5][C:4]=1[CH2:11][NH:12][C:13]1[N:14]=[N:15][CH:16]=[CH:17][CH:18]=1.[F:19][C:20]1[CH:25]=[C:24]([F:26])[C:23]([Cl:27])=[CH:22][C:21]=1[S:28](Cl)(=[O:30])=[O:29]>>[Cl:27][C:23]1[C:24]([F:26])=[CH:25][C:20]([F:19])=[C:21]([S:28]([N:12]([CH2:11][C:4]2[CH:5]=[CH:6][C:7]([O:9][CH3:10])=[CH:8][C:3]=2[O:2][CH3:1])[C:13]2[N:14]=[N:15][CH:16]=[CH:17][CH:18]=2)(=[O:30])=[O:29])[CH:22]=1

Participants

3

Reactant 2

HCID 27735275-Chloro-2,4-difluorobenzenesulphonyl chlorideHCID 63362875HCID 63362875, compound

Product 1

HCID 117653312HCID 117653312, compound

Procedure

The title compound was prepared according to the method described for Preparation 14 using N-[(2,4-dimethoxyphenyl)methyl]pyridazin-3-amine (Preparation 19) and 2,4-difluoro-5-chlorobenzenesulfonyl chloride.

Sources & evidence

ORD record
ord-ddd8ae7873d543eb86ad51cf5a6ff716
Source dataset
uspto-grants-2015_06
Patent number
US09067922B2

Reaction notes

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