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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2178131Generated: October 29, 2026

2,4-Difluorobenzenesulfonyl Chloride → N-(2,4-dimethoxybenzyl)-2,4-difluoro-N-(5-fluoropyridin-2-yl)benzenesulfonamide

https://huagongshe.com/reaction/2178131

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-Difluorobenzenesulfonyl ChlorideHCID 2734273—
ReactantN-(2,4-dimethoxybenzyl)-5-fluoropyridin-2-amineHCID 58042270—
ProductN-(2,4-dimethoxybenzyl)-2,4-difluoro-N-(5-fluoropyridin-2-yl)benzenesulfonamideHCID 117653045—

Reaction Steps

The title compound was prepared according to the method described for Preparation 11 using N-(2,4-dimethoxybenzyl)-5-fluoropyridin-2-amine (Preparation 20) and 2,4-difluorobenzene-1-sulfonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09067922B2
Source datasetuspto-grants-2015_06
ORD IDord-78459321726f429aabf0b0b8a0ad9a4b
Source noteuspto-grants-2015_06