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HRID2178152

反应详情

EQUATION

反应方程式

HRID 2178152 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)c1ccc(OC(F)(F)F)cn1
HCID19860738

5-(Trifluoromethoxy)pyridine-2-carboxylic acid

C7H4F3NO3

结构：C[C@@]1(c2cc(N)ccc2F)C[C@@H](C(F)(F)F)OC(N)=N1
HCID71663148

未命名化合物

PRODUCTS

生成物

1
结构：C[C@@]1(c2cc(NC(=O)c3ccc(OC(F)(F)F)cn3)ccc2F)C[C@@H](C(F)(F)F)OC(N)=N1
HCID71667735

未命名化合物

PROCEDURE

实验过程

The coupling of (4S,6S)-4-(5-amino-2-fluorophenyl)-4-methyl-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-oxazin-2-amine (XI-1) and 5-(trifluoromethoxy)picolinic acid [J. D. Scott et al. WO2011044181 (2011)] following General Procedure G yielded the title compound as a colorless amorphous solid. MS: m/z=481.4 [M+H]+.