HRID2178157

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID58448677

未命名化合物

反应SMILES：C[C@@]1(c2cc(N)ccc2F)C[C@@H](C(F)(F)F)OC(N)=N1

HCID71663148

未命名化合物

PRODUCTS

产物

反应SMILES：CC#CCOc1cnc(C(=O)Nc2ccc(F)c([C@]3(C)C[C@@H](C(F)(F)F)OC(N)=N3)c2)cn1

HCID71652164

未命名化合物

PROCEDURE

实验过程

The coupling of (4S,6S)-4-(5-amino-2-fluorophenyl)-4-methyl-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-oxazin-2-amine (XI-1) and 5-(but-2-ynyloxy)pyrazine-2-carboxylic acid [G. Csjernyik et al. WO2012087237 (2012)] following General Procedure F yielded the title compound as a white solid. MS: m/z=466.5 [M+H]+.