HRID2178163

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID57827466

未命名化合物

结构：NC1=N[C@](CF)(c2cc(N)ccc2F)C[C@@H](C(F)(F)F)O1

HCID86732112

未命名化合物

PRODUCTS

生成物

结构：NC1=N[C@](CF)(c2cc(NC(=O)c3cnc(OCC(F)F)cn3)ccc2F)C[C@@H](C(F)(F)F)O1

HCID71665989

未命名化合物

PROCEDURE

实验过程

The coupling of (4S,6S)-4-(5-amino-2-fluorophenyl)-4-(fluoromethyl)-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-oxazin-2-amine (XI-2) and 5-(2,2-difluoroethoxyl)pyrazine-2-carboxylic acid [Y. Suzuki et al. WO2009091016 (2009)] following General Procedure G yielded the title compound as a colorless solid. MS: m/z=496.6 [M+H]+.