Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2178167Generated: October 29, 2026

Hydrochloric Acid → HCID 89893928, compound

https://huagongshe.com/reaction/2178167

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDiisopropyl EtherHCID 7914—
Reactant1,4-DioxaneHCID 31275—
ReactantHCID 89894133HCID 89894133—
SolventTetrahydrofuranHCID 8028—
ProductHCID 89893928HCID 8989392885%

Reaction Steps

To a solution of (S)-tert-butyl 5-(methylthiomethyl)-2-oxooxazolidin-3-ylcarbamate (374 mg, 1.426 mmol) in THF (2 mL), 4M HCl in dioxane (1.25 mL, 4.99 mmol) was added. The reaction was stirred at r.t. for 4 days and a white solid precipitated. The obtained product was filtered and triturated with hot diisopropyl ether affording the title compound (240 mg, 1.208 mmol). Yield=85%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09067927B2
Source datasetuspto-grants-2015_06
ORD IDord-12d6851a429143f3bb78520d2fbe2e7d
Source noteuspto-grants-2015_06