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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2178171Generated: October 30, 2026

Hydrochloric Acid → HCID 89893940, compound

https://huagongshe.com/reaction/2178171

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1,4-DioxaneHCID 31275—
ReactantHCID 89893984HCID 89893984—
SolventTetrahydrofuranHCID 8028—
ProductHCID 89893940HCID 8989394080%

Reaction Steps

To a solution of (R)-tert-butyl 5-(methylthiomethyl)-2-oxooxazolidin-3-ylcarbamate (429 mg, 1.63 mmol) in THF (3 mL), a solution of 4M HCl in dioxane (1.022 mL, 4.09 mmol) was added. The reaction was stirred at room temperature overnight under nitrogen. Conversion was complete. The title compound, precipitated as a white solid, was filtered, washed with diisopropyl ether and dried under vacuum, (260 mg, 1.31 mmol). Yield=80%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09067927B2
Source datasetuspto-grants-2015_06
ORD IDord-c3405ee9d7404582ac352e01d19dc5d8
Source noteuspto-grants-2015_06