tert-butyl N-(3-hydroxyphenyl)carbamate → HCID 59418745, compound

HRID 2178270Notes

Reaction equation

HRID 2178270 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([NH:8][C:9](=[O:15])[O:10][C:11]([CH3:14])([CH3:13])[CH3:12])[CH:5]=[CH:6][CH:7]=1.[C:16]([O:24][CH2:25][CH2:26]Br)(=[O:23])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[C:16]([O:24][CH2:25][CH2:26][O:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([NH:8][C:9]([O:10][C:11]([CH3:12])([CH3:14])[CH3:13])=[O:15])[CH:3]=1)(=[O:23])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 312485tert-butyl N-(3-hydroxyphenyl)carbamateHCID 5230902-Bromoethyl Benzoate

Product 1

HCID 59418745HCID 59418745, compound

Procedure

2-(3-(tert-Butoxycarbonylamino)phenoxy)ethyl benzoate (42B) was prepared following a similar procedure as that described in example 39, except tert-Butyl 3-hydroxyphenylcarbamate (42A) was used instead of 3-(dimethylamino)phenol and 2-bromoethyl benzoate was used instead of 2-bromoethyl acetate in step 1 of example 39.

Sources & evidence

ORD record
ord-b75ba0eb445b4c729834e93df3e32a21
Source dataset
uspto-grants-2015_06
Patent number
US09067928B2

Reaction notes

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