HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-tert-Butyl-5-isocyanato-1-phenyl-1H-pyrazole → 1-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)-3-(3-(3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yloxy)phenyl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-tert-Butyl-5-isocyanato-1-phenyl-1H-pyrazole | HCID 11096760 | — |
| Reactant | 8-(3-aminophenoxy)pyrido[2,3-b]pyrazin-3(4H)-one | HCID 46901593 | — |
| Product | 1-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)-3-(3-(3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yloxy)phenyl)urea | HCID 46900425 | — |
Reaction Steps
Method F2 was used with 8-(3-aminophenoxy)pyrido[2,3-b]pyrazin-3(4H)-one and 3-tert-butyl-5-isocyanato-1-phenyl-1H-pyrazole to afford the title compound as a slightly yellow solid (97 mg, 62%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08198279B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-b3479c2ae11745b9937f67a4b17213cf |
| Source note | uspto-grants-2012_06 |