Hydrazine → 4-(Morpholin-4-yl)butan-1-amine

HRID 21787Notes

Reaction equation

HRID 21787 reaction equation
[NH2:1]N.[N:3]1([CH2:9][CH2:10][CH2:11][CH2:12]C2C=CC=C3C(NC(=O)C=23)=O)[CH2:8][CH2:7][O:6][CH2:5][CH2:4]1>CO>[N:3]1([CH2:9][CH2:10][CH2:11][CH2:12][NH2:1])[CH2:4][CH2:5][O:6][CH2:7][CH2:8]1

Participants

4

Reactant 2

HCID 9321HydrazineHCID 220025214-Morpholinylbutylphthalimide

Product 1

HCID 2336114-(Morpholin-4-yl)butan-1-amine

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Hydrazine (aqueous solution at 35% by wt.) (0.15 ml; 1.6 mmoles) was added to 4-morpholinylbutylphthalimide (231 mg; 0.8 mmoles) in methanol (5 ml) and the resulting solution was refluxed. Reaction times and process as per Example 1.

Workup

  1. temperaturethe resulting solution was refluxed
  2. customReaction times and process as per Example 1

Sources & evidence

ORD record
ord-f2a073210bba45ae9b448c979d5547fb
Source dataset
uspto-grants-1995_06
Patent number
US05424451

Reaction notes

Loading…