HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxy-1-indanone → 4-Hydroxyindan
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxy-1-indanone | HCID 590547 | — |
| Reactant | HCID 131733031 | HCID 131733031 | — |
| Product | 4-Hydroxyindan | HCID 74233 | — |
Reaction Steps
4-Hydroxy-2,3-dihydro-1H-inden-1-one (W. Liu et al., Org. Lett. 2007, 9, 2915-2918) was reduced with sodium cyanoborohydride/trimethylsilyl chloride to provide 2,3-dihydro-1H-inden-4-ol. This was chlorinated with N-chlorosuccinimide to generate 7-chloro-2,3-dihydro-1H-inden-4-ol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09067934B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-962b26a171434dfda36afff40c47869f |
| Source note | uspto-grants-2015_06 |