5-Fluoro-2-hydroxyphenylboronic acid → HCID 136479233, compound

HRID 2178714Notes

Reaction equation

HRID 2178714 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6](B(O)O)[CH:7]=1.I[C:13]1[CH:18]=[CH:17][N:16]=[C:15]([C:19]([F:22])([F:21])[F:20])[CH:14]=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([OH:11])=[C:6]([C:13]2[CH:18]=[CH:17][N:16]=[C:15]([C:19]([F:22])([F:21])[F:20])[CH:14]=2)[CH:7]=1

Participants

3

Reactant 2

HCID 37724765-Fluoro-2-hydroxyphenylboronic acidHCID 234369404-Iodo-2-(trifluoromethyl)pyridine

Product 1

HCID 136479233HCID 136479233, compound

Procedure

(5-Fluoro-2-hydroxyphenyl)boronic acid and 4-iodo-2-(trifluoromethyl)pyridine were reacted under Suzuki conditions to produce 4-fluoro-2-[2-(trifluoromethyl)pyridin-4-yl]phenol.

Sources & evidence

ORD record
ord-0e5fd708b66e431aa78f5b9ee5ec0fe2
Source dataset
uspto-grants-2015_06
Patent number
US09067934B2

Reaction notes

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