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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2178721Generated: October 28, 2026

Furan → 6,7-Difluoro-1,4-epoxy-1,4-dihydronaphthalene

https://huagongshe.com/reaction/2178721

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFuranHCID 8029—
Reactant1,2-Dibromo-4,5-difluorobenzeneHCID 94949—
ReactantButyllithiumHCID 178418339—
Product6,7-Difluoro-1,4-epoxy-1,4-dihydronaphthaleneHCID 12037073—

Reaction Steps

1,2-Dibromo-4,5-difluorobenzene was treated with n-butyllithium followed by furan to give 6,7-difluoro-1,4-dihydro-1,4-epoxynaphthalene, which was treated with acid to produce 6,7-difluoronaphthalen-1-ol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09067934B2
Source datasetuspto-grants-2015_06
ORD IDord-fbfe2325708f40cb8b69b4105e374e82
Source noteuspto-grants-2015_06