反应详情

Cyclopentylhydrazine (6.5 g, 64.9 mmol) is slowly added to a solution of ethoxymethylenemalononitrile (7.93 g, 64.9 mmol) in 100 ml of methanol at room temperature under argon, subsequently heated under reflux for 3 h and then stirred at room temperature overnight. The solvent is stripped off in a rotary evaporator and the residue is stirred with diethyl ether. The solid is filtered off with suction, washed with diethyl ether and dried under high vacuum.

1. temperaturesubsequently heated
2. temperatureunder reflux for 3 h
3. customThe solvent is stripped off in a rotary evaporator
4. stirringthe residue is stirred with diethyl ether
5. filtrationThe solid is filtered off with suction
6. washwashed with diethyl ether
7. customdried under high vacuum