1-[5-(Trifluoromethyl)-2-vinylphenyl]prop-2-en-1-ol → 6-(trifluoromethyl)-1H-inden-1-ol

Participants

Reaction Conditions

Reaction Steps

To a solution of the 1-[5-(trifluoromethyl)-2-vinylphenyl]prop-2-en-1-ol (462 mg, 2.02 mmol) in methylene chloride (20 mL) under nitrogen was added benzylidene-bis(tricyclohexylphosphine)dichlororuthenium (70 mg, 0.08 mmol). The dark mixture was stirred at 25° C. for 30 min and concentrated. The residue was purified by flash chromatography to give the desired compound (278.1 mg, 68%). LC-MS [M+1]=279.2.

Provenance & Evidence