HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4,6-Dichloro-1,5-naphthyridin-3-yl)ethan-1-one → HCID 117773448, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4,6-Dichloro-1,5-naphthyridin-3-yl)ethan-1-one | HCID 89704977 | — |
| Reactant | HCID 117773949 | HCID 117773949 | — |
| Product | HCID 117773448 | HCID 117773448 | 30.1% |
Reaction Steps
Following general procedure I, 1-(4,6-dichloro-1,5-naphthyridin-3-yl)ethanone (240 mg, 1.0 mmol) was reacted with 4-(((R)-3-fluoropyrrolidin-1-yl)methyl)cyclohexanamine (100 mg, 0.5 mmol) to afford the product (61 mg, 15%) as a brown solid: ESI MS m/z 405 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09067937B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-140e2d996d84404bb48ff74773cbe3da |
| Source note | uspto-grants-2015_06 |