2-Methoxynicotinic acid → (+/-)4-Methoxy-pyridine-2-carboxylic acid (10-ethyl-4-oxo-2-pyrimidin-4-yl-4,6,7,8,9,10-hexahydro-pyrimido[1,2-a]azepin-10-yl)-amide

Beteiligte Stoffe

Reaktionsschritte

By analogy with the method described in example 13 (step 13.5), using (+/−) 10-amino-1 0-ethyl-2-pyrimidin-4-yl-7,8,9,10-tetrahydro-6H-pyrimido[1,2-a]azepin-4-one and 4-methoxy-pyridine-2-carboxylic acid in place of (+)10-amino-10-methyl-2-pyrimidin-4-yl-7,8,9,10-tetrahydro-6H-pyrimido[1,2-a]azepin-4-one and 2-methoxy nicotinic acid, 37 mg (31%) of the compound was obtained as a white solid.

Herkunft & Nachweise