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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2179060Generated: October 29, 2026

HCID 59820596, compound → HCID 71575912, compound

https://huagongshe.com/reaction/2179060

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59820596HCID 59820596—
Reactant5-tert-Butyl-7-(3,3-difluoro-pyrrolidin-1-yl)-2-ethyl-2H-[1,2,3]triazolo[4,5-d]pyrimidineHCID 71576307—
ReactantHCID 178441789HCID 178441789—
ProductHCID 71575912HCID 71575912—

Reaction Steps

In analogy to the procedure described for the synthesis of 5-tert-butyl-7-(3,3-difluoro-pyrrolidin-1-yl)-2-ethyl-2H-[1,2,3]triazolo[4,5-d]pyrimidine (example 3, step b), the title compound was prepared from 5-tert-butyl-7-(3,3-difluoropyrrolidin-1-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine and 3-(iodomethyl)-4-methyl-5-(methylsulfonyl)-4H-1,2,4-triazole and isolated as white solid. MS (m/e): 456.3 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09067943B2
Source datasetuspto-grants-2015_06
ORD IDord-6dbe8efb56664de7899f175c1afcf0a9
Source noteuspto-grants-2015_06