HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(chloromethyl)-1,3-dimethyl-1H-pyrazole → HCID 89586784, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(chloromethyl)-1,3-dimethyl-1H-pyrazole | HCID 4961270 | — |
| Reactant | 5-tert-Butyl-7-(3,3-difluoro-pyrrolidin-1-yl)-2-ethyl-2H-[1,2,3]triazolo[4,5-d]pyrimidine | HCID 71576307 | — |
| Reactant | HCID 178441789 | HCID 178441789 | — |
| Product | HCID 89586784 | HCID 89586784 | — |
Reaction Steps
In analogy to the procedure described for the synthesis of 5-tert-butyl-7-(3,3-difluoro-pyrrolidin-1-yl)-2-ethyl-2H-[1,2,3]triazolo[4,5-d]pyrimidine (example 3, step b), the title compound was prepared from 5-tert-butyl-7-(3,3-difluoropyrrolidin-1-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine and 5-(chloromethyl)-1,3-dimethyl-1H-pyrazole and isolated as light yellow gum. MS (m/e): 391.3 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09067943B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-769b92c84538448390e1d989bda5f129 |
| Source note | uspto-grants-2015_06 |