HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Chloromethyl)-5-methyl-1,3,4-oxadiazole → HCID 89586455, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Chloromethyl)-5-methyl-1,3,4-oxadiazole | HCID 3826620 | — |
| Reactant | (S)-1-[5-tert-Butyl-2-(4-methyl-furazan-3-ylmethyl)-2H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-pyrrolidin-3-ol | HCID 71575968 | — |
| Reactant | HCID 178441791 | HCID 178441791 | — |
| Product | HCID 89586455 | HCID 89586455 | — |
Reaction Steps
In analogy to the procedure described for the synthesis of (S)-1-[5-tert-Butyl-2-(4-methyl-furazan-3-ylmethyl)-2H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-pyrrolidin-3-ol (example 73), the title compound was prepared from Trifluoro-acetic acid (S)-1-(5-tert-butyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)-pyrrolidin-3-yl-ester and 2-(chloromethyl)-5-methyl-1,3,4-oxadiazole and isolated as light yellow gum. MS (m/e): 359.5 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09067943B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-6f8ff39fc622436eac91f7e904ae4aaa |
| Source note | uspto-grants-2015_06 |