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HRID2179110

反应详情

EQUATION

反应方程式

HRID 2179110 的结构方程式

REACTANTS

反应物

3
结构：Cn1nnnc1CCl
HCID12205086

5-(chloromethyl)-1-methyl-1H-1,2,3,4-tetrazole

C3H5ClN4

结构：Cn1nnnc1Cn1nnc2c(N3CC[C@@H](O)C3)nc(C(C)(C)C)nc21
HCID86296050

未命名化合物

结构：CC(C)(C)c1nc(N2CCC(O)C2)c2nnn(Cc3ccccc3)c2n1
HCID86683389

未命名化合物

PRODUCTS

生成物

1
结构：Cn1nnnc1Cn1nc2nc(C(C)(C)C)nc(N3CCC(O)C3)c2n1
HCID89586557

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described for the synthesis of (R)-1-(5-tert-butyl-3-((1-methyl-1H-tetrazol-5-yl)methyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)pyrrolidin-3-ol (example 113, b) 1-(3-Benzyl-5-tert-butyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)-pyrrolidin-3-ol was hydrogenated and subsequently reacted with 5-(chloromethyl)-1-methyl-1H-tetrazole and isolated as light yellow oil. MS (m/e): 359.3 (MH+).

WORKUP

后处理

  1. customisolated as light yellow oil