Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2179119Generated: October 31, 2026

1-(Bromomethyl)-2-methanesulfonylbenzene → HCID 89586291, compound

https://huagongshe.com/reaction/2179119

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Bromomethyl)-2-methanesulfonylbenzeneHCID 18922474—
Reactant5-tert-Butyl-7-(3,3-difluoro-pyrrolidin-1-yl)-2-ethyl-2H-[1,2,3]triazolo[4,5-d]pyrimidineHCID 71576307—
ReactantHCID 178475050HCID 178475050—
ProductHCID 89586291HCID 89586291—

Reaction Steps

In analogy to the procedure described for the synthesis of 5-tert-butyl-7-(3,3-difluoro-pyrrolidin-1-yl)-2-ethyl-2H-[1,2,3]triazolo[4,5-d]pyrimidine (example 3, step b), the title compound was prepared from N—{(S)-1-[5-((S)-2,2,2-Trifluoro-1-methyl-ethoxy)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]-pyrrolidin-3-yl}-acetamide and 1-(bromomethyl)-2-(methylsulfonyl)benzene. MS (m/e): 528.5 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09067943B2
Source datasetuspto-grants-2015_06
ORD IDord-e33c8c85b69a45d0b9af7378130af77c
Source noteuspto-grants-2015_06