HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetanilide → N-Phenyl-N-thiophen-3-yl-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetanilide | HCID 904 | — |
| Reactant | 3-Bromothiophene | HCID 13383 | — |
| Product | N-Phenyl-N-thiophen-3-yl-acetamide | HCID 16640263 | 82% |
Reaction Steps
Using general procedure C, 3-bromothiophene was coupled with acetanilide with the reaction time of 15 h. Chromatography gave 178 mg (82%) of the title compound as an oil. 1H NMR (CDCl3, 300 MHz): δ 7.44 (br s, 3H), 7.28 (s, 2H), 7.18 (s, 2H), 6.94 (d, 1H, J=4.8 Hz), 1.99 (br s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09067955B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-a4e39be0640148a290f73c4cedccdb50 |
| Source note | uspto-grants-2015_06 |