Hydrochloric Acid → HCID 68108558, compound

Participants

Reaction Steps

The product of step B (30 mg, 0.08 mmol) was converted to hydrochloride salt by dissolving in methanol and treating with 1.25 M HCl in methanol. The reaction mixture was concentrated in vacuo to give 8-(3,5-dichlorophenylsulfonyl)-1,2,3,4-tetrahydrobenzofuro[3,2-c]pyridine hydrochloride (32 mg, 98%, AUC HPLC 98.3%) as a white solid: mp 312-315° C.; 1H NMR (DMSO-d6, 300 MHz) δ 9.43 (br s, 2H), 8.50 (d, J=1.8 Hz, 1H), 8.06-7.96 (m, 4H), 7.86 (d, J=8.7 Hz, 1H), 4.40 (s, 2H), 3.54 (t, J=6.0 Hz, 2H), 3.17-3.07 (m, 2H); APCI MS m/z 382 [M+H]+.

Provenance & Evidence